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Original Article
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| Impact of sex on the early and long-term outlook of patients undergoing carotid artery stenting with a single embolic protection device-stent combo | ||||||
| Arturo Giordano1, Paolo Ferraro1, Nicola Corcione1, Michele Polimeno1, Stefano Messina1, Gabriele Giordano1, Rosario Mancusi1, Raffaella Avellino1, Giacomo Frati2, Giuseppe Biondi-Zoccai2 | ||||||
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1Unità Operativa di Interventistica Cardiovascolare, Presidio Ospedaliero Pineta Grande, Castel Volturno, and Unità Operativa di Emodinamica, Casa di Salute Santa Lucia, San Giuseppe Vesuviano Italy.
2Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy. | ||||||
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| Giordano A, Ferraro P, Corcione N, Polimeno M, Messina S, Giordano G, Mancusi R, Avellino R, Frati G, Biondi-Zoccai B. Impact of sex on the early and long-term outlook of patients undergoing carotid artery stenting with a single embolic protection device-stent combo. Edorium J Cardiol 2015;2:9–15. |
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Abstract
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Aims:
Whether men and women benefit similarly from carotid artery stenting (CAS) remains uncertain. We hypothesized that CAS, especially when performed with the same combination of embolic protection device (EPD) and stent, may have a different risk-benefit profile in men and women.
Methods: We retrospectively collected data on all patients undergoing CAS with the Angioguard EPD and Precise RX stent. A total of 447 patients were included, 285 (64%) men and 162 (36%) women. Results: Despite several baseline, lesion and procedural differences, procedural success and clinical outcomes were similar (all p > 0.05), at both discharge and long-term follow-up (19±21 months). Specifically, the composite of death, myocardial infarction, stroke or transient ischemic attack occurred in 5 (2%) men and 2 (1%) women at discharge, and 32 (11%) men and 12 (7%) women at follow-up (both p > 0.05). Even after propensity score matching, no significant differences were found (all p > 0.05). Conclusion: In conclusion, despite several baseline disparities, there are no differences in the early and long-term incidence of adverse events in men versus women undergoing CAS. | |
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Keywords:
Carotid artery disease, Carotid artery stenting, Gender, Sex, Stroke
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Author Contributions:
Arturo Giordano – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Paolo Ferraro – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Nicola Corcione – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Michele Polimeno – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Stefano Messina – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Gabriele Giordano – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Rosario Mancusi – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Raffaella Avellino – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Giacomo Frati – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Giuseppe Biondi-Zoccai – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2015 Arturo Giordano et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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